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Bootstrap is a powerful, open-source front-end framework for creating responsive websites quickly. Developed by Twitter, it features a 12-column grid system, pre-styled components, and extensive documentation. To get started, include Bootstrap via CDN, build a basic layout with its grid system, and customize with CSS. Key tips include keeping code clean, leveraging utility classes, and staying updated with new versions. For further learning, check out the https://getbootstrap.com/docs/, https://github.com/twbs/bootstrap, and https://www.w3schools.com/bootstrap4/.