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Sufficing the suffice ( part 3 ) Now a thrilling movie which supposedly took a great start is pacing down to understand as to why do we even consider going herbal. A herbal combination imply natural flavonoids, phenolics, terpenoids, lignans, and a vast diversity available to humans, and require extensive testing and optimization to serve purpose. Generally, semisynthesis from natural chemicals give compounds for commercial use. Synthetic chemicals used in skin cosmetics bear their objective in dissolving tissue melanin to some extent. Other chemicals contribute to fragrance, germ killing, etcetera. Nature derived herbal combinations have a optimum range, where the combination exhibit superior activity. For example, quercetin might be an antioxidant of choice, but when applied below or above it's optimum range, can cause extensive harm or else will not exhibit any activity.